Skip to main content

Table 1 Cytotoxic effects of the tested compounds

From: Isolation of anticancer constituents from flos genkwa (Daphne genkwaSieb.et Zucc.) through bioassay-guided procedures

 

Huh 7

A 2058

B 16

231

MCF-7

COLO 205

A 549

AGS

HT-29

 

IC50μg/mL

Yuanhuacine

>60

15

18

20

15

3

>60

17

23

Genkwanine III

>60

54

>60

>60

>60

>60

34

>60

>60

Genkwanine VIII

>60

58

>60

>60

48

34

>60

12

29

Yuanhuadine

13

12

11

19

10

2

3

16

13

Daphnoretin

48

17

13

>60

>60

>60

>60

34

>60

Genkwanin

56

>60

>60

>60

>60

>60

>60

3'-hydroxygenkwanin

>60

21

>60

40

>60

43

>60

Tiliroside

>60

>60

>60

43

>60

>60

>60

Apigenin

>60

>60

>60

>60

>60

>60

>60

Pinoresinol

>60

>60

>60

>60

>60

>60

>60

Syringaresinol

>60

>60

>60

>60

57

>60

>60

Lariciresinol

>60

>60

>60

>60

>60

>60

>60

Aurantiamide acetate

>60

>60

56

>60

>60

>60

>60

  1. Table 1: Inhibitory effects of the compounds from dichloromethane fraction of the Flos Genkwa on the proliferation of MDA-MB-231, Huh 7, AGS, Colo 205, MCF-7, HT-29, A 549, A 2058 and B 16 cells. Cells were treated with 0–20 μg/mL of extracts for 24 h.