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Table 1 Biological and deposited mass values at all airflows tested

From: Characterisation of a Vitrocell® VC 10 in vitrosmoke exposure system using dose tools and biological analysis

 

NRU

AMES

 

(184 minute exposure)

(24 minute exposure)

 

Correlation of R2 = 0.842

Correlation of R2 = 0.763

Airflow (L/min)

Reciprocal of airflow (1/airflow (L/min))

Mean deposited mass for NRU exposure μg/cm2 ± SD

Mean% relative cell survival ± SD

Mean deposited mass for Ames exposure μg/cm2 ± SD

Mean revertant fold increase ± SD

Mean total revertants ± SD

1.0

1.000

22.8 ± 1.7

−2.5 ± 3.3

2.30 ± 0.14

5.9 ± 1.6

78.6 ± 20.6

4.0

0.250

3.5 ± 0.1

16.7 ± 7.4

0.50 ± 0.10

4.0 ± 0.9

53.1 ± 9.6

8.0

0.125

0.8 ± 0.1

69.9 ± 13.0

0.09 ± 0.02

2.2 ± 0.4

30.2 ± 4.1

12.0

0.080

0.1 ± 0.1

96.8 ± 10.1

0.03 ± 0.01

1.6 ± 0.5

21.2 ± 5.0

  1. Deposition data was obtained in situ from a 184 and 24 minute smoke exposure for NRU (Correlation R2 = 0.847) and the Ames assay (Correlation R2 = 0.763) respectively.