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Table 1 Biological and deposited mass values at all airflows tested

From: Characterisation of a Vitrocell® VC 10 in vitrosmoke exposure system using dose tools and biological analysis

  NRU AMES
  (184 minute exposure) (24 minute exposure)
  Correlation of R2 = 0.842 Correlation of R2 = 0.763
Airflow (L/min) Reciprocal of airflow (1/airflow (L/min)) Mean deposited mass for NRU exposure μg/cm2 ± SD Mean% relative cell survival ± SD Mean deposited mass for Ames exposure μg/cm2 ± SD Mean revertant fold increase ± SD Mean total revertants ± SD
1.0 1.000 22.8 ± 1.7 −2.5 ± 3.3 2.30 ± 0.14 5.9 ± 1.6 78.6 ± 20.6
4.0 0.250 3.5 ± 0.1 16.7 ± 7.4 0.50 ± 0.10 4.0 ± 0.9 53.1 ± 9.6
8.0 0.125 0.8 ± 0.1 69.9 ± 13.0 0.09 ± 0.02 2.2 ± 0.4 30.2 ± 4.1
12.0 0.080 0.1 ± 0.1 96.8 ± 10.1 0.03 ± 0.01 1.6 ± 0.5 21.2 ± 5.0
  1. Deposition data was obtained in situ from a 184 and 24 minute smoke exposure for NRU (Correlation R2 = 0.847) and the Ames assay (Correlation R2 = 0.763) respectively.