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Table 1 Thermoanalytical data of the two active substances and the used excipients

From: Thermal behaviour of procaine and benzocaine Part II: compatibility study with some pharmaceutical excipients used in solid dosage forms

Substance

TG/DTG curves

HF curves

Nature of the process

Tonset/°C

Tpeak DTG/°C

Tonset/°C

Tpeak DSC/°C

Procaine

194.5

281

148; 240

156; 279

melting; decomposition

Benzocaine

130

241

77; 147

90; 246

melting; decomposition

MC

40; 295

55; 354

50

125

dehydratation; decomposition

L

75; 218

86; 158; 317

254; 367

270; 409

dehydratation; decomposition

MS

50; 280

78; 362

50

117

dehydratation; decomposition

Talc

--

--

--

--

--