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Table 1 Matrix of the central composite design (CCD), experimental and predicted data

From: Influence of astaxanthin, emulsifier and organic phase concentration on physicochemical properties of astaxanthin nanodispersions

Run number ax1,% ax2,% ax3,% Particle size (nm) PDI Astaxanthin loss (wt %)
bYexp. cYpre. bYexp. cYpre. bYexp. cYpre.
1cp 0.20 2.0 20 97.49 93.20 0.382 0.375 12.46 17.59
2cp 0.20 2.0 20 95.83 93.20 0.383 0.375 15.11 17.59
3 0.30 1.0 30 103.90 103.91 0.300 0.310 25.41 24.90
4 0.10 1.0 10 90.29 93.63 0.246 0.241 36.27 35.32
5 0.10 3.0 30 139.10 137.65 0.485 0.501 4.33 0.65
6 0.30 3.0 10 107.57 112.60 0.526 0.519 26.75 25.07
7 0.10 1.0 30 99.43 94.75 0.241 0.223 38.64 38.26
8 0.30 1.0 10 133.20 135.00 0.310 0.306 19.00 21.43
9cp 0.20 2.0 20 98.35 99.93 0.374 0.364 18.04 17.32
10cp 0.20 2.0 20 95.98 99.93 0.387 0.364 21.59 17.32
11 0.30 3.0 30 137.88 134.89 0.549 0.566 10.50 12.18
12 0.10 3.0 10 109.73 110.07 0.393 0.432 10.98 12.23
13 0.38 2.0 20 130.97 129.00 0.443 0.445 17.99 18.57
14cp 0.20 2.0 20 96.98 97.35 0.372 0.376 19.81 19.04
15 0.20 2.0 38 120.02 125.26 0.388 0.399 15.65 14.80
16 0.20 2.0 2 121.97 116.30 0.341 0.353 26.76 23.29
17 0.20 3.8 20 129.96 129.62 0.672 0.644 13.69 15.16
18 0.02 2.0 20 104.83 106.37 0.315 0.308 15.34 19.52
19cp 0.20 2.0 20 96.41 97.35 0.384 0.376 19.53 19.04
20 0.20 0.2 20 99.14 99.05 0.209 0.223 47.56 46.91
  1. cp center point.
  2. ax1, x2 and x3 are astaxanthin concentration, emulsifier concentration and organic phase concentration, respectively.
  3. bYexp. experimental data.
  4. cYpre. predicted data.