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Table 1 Matrix of the central composite design (CCD), experimental and predicted data

From: Influence of astaxanthin, emulsifier and organic phase concentration on physicochemical properties of astaxanthin nanodispersions

Run number

ax1,%

ax2,%

ax3,%

Particle size (nm)

PDI

Astaxanthin loss (wt %)

bYexp.

cYpre.

bYexp.

cYpre.

bYexp.

cYpre.

1cp

0.20

2.0

20

97.49

93.20

0.382

0.375

12.46

17.59

2cp

0.20

2.0

20

95.83

93.20

0.383

0.375

15.11

17.59

3

0.30

1.0

30

103.90

103.91

0.300

0.310

25.41

24.90

4

0.10

1.0

10

90.29

93.63

0.246

0.241

36.27

35.32

5

0.10

3.0

30

139.10

137.65

0.485

0.501

4.33

0.65

6

0.30

3.0

10

107.57

112.60

0.526

0.519

26.75

25.07

7

0.10

1.0

30

99.43

94.75

0.241

0.223

38.64

38.26

8

0.30

1.0

10

133.20

135.00

0.310

0.306

19.00

21.43

9cp

0.20

2.0

20

98.35

99.93

0.374

0.364

18.04

17.32

10cp

0.20

2.0

20

95.98

99.93

0.387

0.364

21.59

17.32

11

0.30

3.0

30

137.88

134.89

0.549

0.566

10.50

12.18

12

0.10

3.0

10

109.73

110.07

0.393

0.432

10.98

12.23

13

0.38

2.0

20

130.97

129.00

0.443

0.445

17.99

18.57

14cp

0.20

2.0

20

96.98

97.35

0.372

0.376

19.81

19.04

15

0.20

2.0

38

120.02

125.26

0.388

0.399

15.65

14.80

16

0.20

2.0

2

121.97

116.30

0.341

0.353

26.76

23.29

17

0.20

3.8

20

129.96

129.62

0.672

0.644

13.69

15.16

18

0.02

2.0

20

104.83

106.37

0.315

0.308

15.34

19.52

19cp

0.20

2.0

20

96.41

97.35

0.384

0.376

19.53

19.04

20

0.20

0.2

20

99.14

99.05

0.209

0.223

47.56

46.91

  1. cp center point.
  2. ax1, x2 and x3 are astaxanthin concentration, emulsifier concentration and organic phase concentration, respectively.
  3. bYexp. experimental data.
  4. cYpre. predicted data.