Skip to main content

Table 6 In vitro cytotoxicity of acridone 1, 4, 7 and 8

From: Aromatase and glycosyl transferase inhibiting acridone alkaloids from fruits of Cameroonian Zanthoxylumspecies

 

IC50expressed in μM

Compounds

WRL-68

CaCO2

MCF-7

PC-3

1

86

>300

229

272

4

>300

>300

>300

>300

7

>300

>300

>300

>300

8

>300

>300

205

>300

Doxorubicin

1.4

6.0

3.6

8.6

  1. WRL-68 = Liver cancer cell lines, CaCO2 = colon cancer, MCF-7 = breast cancer, PC-3 = prostate cancer. Doxorubicin Sigma D-1515 is the standard used.