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Table 6 In vitro cytotoxicity of acridone 1, 4, 7 and 8

From: Aromatase and glycosyl transferase inhibiting acridone alkaloids from fruits of Cameroonian Zanthoxylumspecies

  IC50expressed in μM
Compounds WRL-68 CaCO2 MCF-7 PC-3
1 86 >300 229 272
4 >300 >300 >300 >300
7 >300 >300 >300 >300
8 >300 >300 205 >300
Doxorubicin 1.4 6.0 3.6 8.6
  1. WRL-68 = Liver cancer cell lines, CaCO2 = colon cancer, MCF-7 = breast cancer, PC-3 = prostate cancer. Doxorubicin Sigma D-1515 is the standard used.