Skip to main content

Table 3 Cytotoxicity a activities of compounds 7f and 7g in Vero and MRC-5 cells

From: Synthesis and structure−activity relationship of 8-substituted protoberberine derivatives as a novel class of antitubercular agents

Compd

Vero

 

MRC-5

 
 

CC50 (ug/ml)

SIb

CC50 (ug/ml)

SI

7f

14.72 ± 2.02

7.37

10.18 ± 2.78

5.09

7g

5.15 ± 1.29

10.3

8.78 ± 0.48

17.6

  1. a: Cytotoxic concentration required to inhibit Vero or MRC-5 cell growth by 50%.
  2. b: Selectivity index (SI) value equaled to CC50/MIC.
Back to article page

BMC Chemistry

ISSN: 2661-801X

Contact us