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Table 2 In vitro anticholinesterase activities of compounds 1–4

From: Acetyl and butyryl cholinesterase inhibitory sesquiterpene lactones from Amberboa ramosa

 

IC 50 (μM) ± SEMa

 

S. No

Compounds

AChE

BChE

1

Amberbin C (1)

1.1 ± 0.08

17.9 ± 0.05

2

Amberin (2)

17.5 ± 0.01

2.7 ± 0.02

3

Amberbin A (3)

8.6 ± 0.15

4.8 ± 0.15

4

Amberbin B (4)

0.91 ± 0.015

2.5 ± 0.15

5

Galanthamineb

0.5 ± 0.01

8.2 ± 0.02

6

Eserineb

0.04 ± 0.0001

0.82 ± 0.001

  1. a Standard error of the mean of five assays; b positive control used in the assays.