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Table 2 Influence of the organic solvent on the synthesis of D- isoascorbyl palmitate

From: D-isoascorbyl palmitate: lipase-catalyzed synthesis, structural characterization and process optimization using response surface methodology

Solvent

Log P

Conversion rate (%)a

Ethanol

−0.24

0

Acetone

−0.23

57.8 ± 1.8

2-Methyl-2-butanol

1.31

49.6 ± 2.3

Chloroform

2

0

Petroleum ether

2.62

0

N-hexane

3.53

25.28 ± 3.9

  1. a: D-isoascorbic 2.5 mmol palmitic acid 10 mmol (Molar ratio was 1:4), Novozym 435 load: 15% (weight % of substrates), temperature 50°C, 50 g/L molecular sieve 4 Å and 200 rpm speed for 24 h.