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Table 2 Influence of the organic solvent on the synthesis of D- isoascorbyl palmitate

From: D-isoascorbyl palmitate: lipase-catalyzed synthesis, structural characterization and process optimization using response surface methodology

Solvent Log P Conversion rate (%)a
Ethanol −0.24 0
Acetone −0.23 57.8 ± 1.8
2-Methyl-2-butanol 1.31 49.6 ± 2.3
Chloroform 2 0
Petroleum ether 2.62 0
N-hexane 3.53 25.28 ± 3.9
  1. a: D-isoascorbic 2.5 mmol palmitic acid 10 mmol (Molar ratio was 1:4), Novozym 435 load: 15% (weight % of substrates), temperature 50°C, 50 g/L molecular sieve 4 Å and 200 rpm speed for 24 h.