Table 4 Robustness study of moxifloxacin
Chromatographic conditions | Assay % | tR(min) | Theoretical plates | Tailing |
|---|---|---|---|---|
Methanol:buffer (64:36) | 99.1 | 3.241 | 4347 | 1.26 |
Methanol:buffer (62:38) | 102.0 | 3.446 | 4328 | 1.26 |
Methanol:buffer (60:40) | 100.5 | 3.615 | 4498 | 1.24 |
Flow rate (1.3 mL/min) | 100.8 | 3.825 | 4448 | 1.26 |
Flow rate (1.5 mL/min) | 98.4 | 3.447 | 4319 | 1.26 |
Flow rate (1.7 mL/min) | 98.2 | 3.089 | 4358 | 1.26 |
Buffer (pH 2.6) | 101.0 | 3.442 | 4348 | 1.24 |
Buffer (pH 2.8) | 100.9 | 3.446 | 4442 | 1.26 |
Buffer (pH 3.0) | 101.2 | 3.443 | 4488 | 1.24 |