Table 2 Assay results for the determination of the studied drugs in their synthetic mixture and co-formulated tablets.
Sample | Concentration taken (μg/mL) | Concentration found (μg/mL) | % Found | Reference method [14] | ||||
|---|---|---|---|---|---|---|---|---|
1- Synthetic mixture(a) | ROS | GLM | ROS | GLM | ROS | GLM | ROS | GLM |
0.25 | 0.125 | 0.249 | 0.127 | 99.60 | 101.60 | 99.10 | 100.27 | |
0.5 | 0.25 | 0.501 | 0.251 | 100.20 | 100.40 | 100.64 | 98.18 | |
1.0 | 0.5 | 1.013 | 0.506 | 101.30 | 101.20 | 98.00 | 99.73 | |
5.0 | 2.5 | 4.966 | 0.473 | 99.32 | 98.92 | |||
10.0 | 5.0 | 10.005 | 5.014 | 100.05 | 100.28 | |||
15.0 | 7.5 | 15.131 | 7.473 | 100.87 | 99.64 | |||
25.0 | 12.5 | 25.047 | 12.473 | 100.19 | 99.78 | |||
X' | 100.22 | 100.26 | 99.25 | 99.06 | ||||
SD | 0.68 | 0.92 | 1.33 | 1.08 | ||||
%RSD | 0.68 | 0.92 | ||||||
±%Error | 0.26 | 0.35 | ||||||
t- test | 1.58 | 1.80 | ||||||
F- test | 3.83 | 1.37 | ||||||
2-AvandarylTM tablets(b) (4 mg ROS + 2 mg GLM/tablet) | 0.25 | 0.125 | 0.253 | 0.123 | 101.20 | 98.40 | 98.10 | 101.56 |
1.0 | 0.5 | 0.994 | 0.511 | 99.4 | 102.20 | 99.27 | 98.50 | |
5.0 | 2.5 | 5.038 | 2.543 | 100.76 | 101.72 | 100.71 | 100.40 | |
10.0 | 5.0 | 10.215 | 4.946 | 102.15 | 98.92 | |||
X' | 100.88 | 100.31 | 99.36 | 100.15 | ||||
SD | 1.14 | 1.93 | 1.31 | 1.54 | ||||
%RSD | 1.14 | 1.93 | ||||||
±%Error | 0.57 | 0.97 | ||||||
t- test | 1.65 | 0.12 | ||||||
F- test | 1.32 | 1.32 | ||||||