Skip to main content

Table 1 Analytical performance data for the determination of the studied drugs by the proposed method.

From: Development and validation of a repharsed phase- HPLC method for simultaneous determination of rosiglitazone and glimepiride in combined dosage forms and human plasma

Parameter ROS GLM
Linearity range (μg/mL) 0.10-25 0.125-12.5
Intercept (a) -5.9 × 10-4 -1.7 × 10-3
Slope (b) 0.119 0.122
Correlation coefficient (r) 0.9999 0.9999
S.D. of residuals (S y/x ) 6.90 × 10-3 2.68 × 10-3
S.D. of intercept (S a ) 1.58 × 10-3 1.39 × 10-3
S.D. of slope (S b ) 2.88 × 10-4 2.36 × 10-4
Percentage relative standard deviation, % RSD 0.80 0.92
Percentage relative error, % Error 0.28 0.35
Limit of detection, LOD (μg/mL) 0.04 0.04
Limit of quantitation, LOQ (μg/mL) 0.13 0.11