Table 1 Yields and melting points of 2-aryl-3-hydroxymethyl imidazo[1,2-a]pyridines 6
From: Fluorescent property of 3-hydroxymethyl imidazo[1,2-a]pyridine and pyrimidine derivatives
Compound 6 | Aryl | Yield (%) | Mp (°C) Experimental | Mp (°C) Literature* |
|---|---|---|---|---|
a | C6H5 | 70% | 202 - 203 | >212 |
b | 4’Cl-C6H4 | 61.3% | 229 - 230 | >240 |
c | 4’F-C6H4 | 70.3% | 154 - 155 | 153 - 155 |
d | 4’CH3-C6H4 | 76.7% | 274 - 275 | >290 |
e | 4’CH3O-C6H4 | 66.7% | 166 - 167 | 165 - 167 |
f | 3’,4’di-CH3O-C6H3 | 71% | 171 - 172 | 170 - 172 |
g | 4’NO2-C6H4 | 70% | 225 - 226 | 224 – 226 |