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Table 1 Results from Friedel-Crafts acetylation of 3,3′-dimethylbiphenyl using the Perrier addition procedure a

From: A reactivity-selectivity study of the Friedel-Crafts acetylation of 3,3′-dimethylbiphenyl and the oxidation of the acetyl derivatives

Run No Solvent Temp (°C) Yield (%) Isomer distribution (%) 4-Ac
1 ClCH2CH2Cl 25 56.5 100
2 CS2 25 55.1 100
3 CH3NO2 25 57.5 100
4 ClCH2CH2Cl 45 51.9 100
5 CS2 45 60.8 100
6 CH3NO2 45 47.2 100
  1. a The 3,3′-dmbp:AcCl:AlCl3 molar ratio was 1:1:1 and the reaction time was 3 h.