Three-dimensional quantitative structure activity relationship (QSAR) of cytotoxic active 3,5-diaryl-4,5-dihydropyrazole analogs: a comparative molecular field analysis (CoMFA) revisited study

Table 4 Summary of COMFA results*

r²Conventional	0.895
Standard error of estimate	0.163
F Value	(n1 = 6, n2 = 23) 24.478
P Value	0.000
r² cross-validated	0.568
Standard error of predictions	0.21
No. of components	6
Steric contribution	0.454
Electrostatic contribution	0.546
Mean PIC₅₀	−0.8896
Mean predicted PIC₅₀	−0.799

^*Results from leave one out (LOO) cross validation analysis using six components.

ISSN: 2661-801X