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Table 3 Summary of the generated pharmacophores of the Antiproliferative activities of the synthesized Schiff bases against MCF-12A cell line

From: Schiff bases of indoline-2,3-dione (isatin) with potential antiproliferative activity

Hypothesis

Features*

Rank score

Hypo1

HHAAADD

0.8665

Hypo2

HHAAADD

0.8657

Hypo3

HHAAADD

0.8656

Hypo4

HHAAADD

0.8652

Hypo5

HHAAADD

0.8651

Hypo6

HHAAADD

0.8624

Hypo7

HHAAADD

0.8622

Hypo8

HHRAAADD

0.8578

Hypo9

HHRAAADD

0.8550

Hypo10

HHRAAADD

0.8483

  1. *H hydrophobic, R aromatic ring, A hydrogen bond acceptor, D hydrogen bond donor.