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Table 3 Analysis of MLT in commercial tablets by the proposed and reference methods

From: New spectrofluorimetric methods for determination of melatonin in the presence of N-{2-[1-({3-[2-(acetylamino)ethyl]-5-methoxy-1H-indol-2-yl}methyl)-5-methoxy-1H-indol-3-yl]- ethyl}acetamide: a contaminant in commercial melatonin preparations

Method

Second derivative method

PCR method

PLS method

Reference method24

Mean ± SDa

100.51 ± 2.663

100.99 ± 1.483

100.79 ± 1.479

100.59 ± 3.379

n

5

5

5

5

t test (2.306)

0.041

0.247

0.124

-

F (6.388)

1.610

5.187

5.220

-

  1. a Mean ± standard deviation.
  2. Values in parentheses are theoretical values for t and F at P = 0.05.