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Table 3 Application of the proposed and comparison methods to the determination of ALD in pure form

From: Validated spectrophotometric methods for determination of Alendronate sodium in tablets through nucleophilic aromatic substitution reactions

Parameter

Method I

Method II

Method III

Comparison Method (7)

No of experiments

6

5

6

3

x ± S.D.

100.47 ± 1.12

100.17 ± 1.21

99.23 ± 1.26

100.55 ± 1.30

t

0.096 (2.365)*

0.420 (2.447)*

1.471 (2.365)*

 

F

1.347 (5.786)*

1.154 (6.944)*

1.064 (5.786)*

 
  1. Each result is the average of three separate determinations
  2. *Values between brackets are the tabulated t and F values, at P = 0.05 [45].
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BMC Chemistry

ISSN: 2661-801X

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