Rapid determination of natural steroidal hormones in saliva for the clinical diagnoses

BMC Chemistry

Table 4 Comparison of analytical methods for determining natural steroidal compounds in saliva

Ref	Preparation method	Instrument	The limit of quantification (μg/L)
			E1	E2	E3	P	T
Hogg et al. 2005 [21]	SPE	LC-MS/MS	-	-	-	-	0.5
Matsui et al. 2009 [12]	SPE	LC-MS/MS	-	-	-	-	0.005
Shibayama et al. 2009 [4]	SPE	LC-MS/MS	-	-	-	-	0.010
Gould et al. 1986 [23]	IA	GC-MS	-	-	-	-	0.0013*
De Boever et al. 1988 [18]	-	EIA	-	-	0.09*	-	-
Kivlighan et al. 2005 [16]		EIA		0.001*		0.005*
This study	LLE	GC-MS	0.003	0.002	0.3	0.003	0.003

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