Figure 4

EF and corresponding percentages of active compounds with pharmacophore-based VS using the fourth and first datasets. (a-1) EF of pharmacophore-based VS with the fourth experimental dataset. (a-2) The corresponding percentages of active compounds with the fourth experimental dataset. (b-1) Enrichment factor when screening the first experimental dataset. (b-2) The corresponding percentages of active compounds when screening the first experimental dataset. The plot shows the results with four ligand groups: 32 ligands (blue); 16 ligands (red); 8 ligands (green); and 4 ligands (purple).