Figure 5
From: Cellular responses induced by Cu(II) quinolinonato complexes in human tumor and hepatic cells
The resistance factors of Cu(II) complexes, expressed as the IC 50 (A2780cis)/IC 50 (A2780) ratios. The graphical view of the IC50(A2780cis)/IC50(A2780) ratios calculated from the obtained IC50 (μM) values of the in vitro cytotoxicity for complexes 1 and 3–6, and cisplatin against the ovarian carcinoma (A2780) and ovarian carcinoma cisplatin resistant (A2780cis) human cancer cell lines. The symbol (***) denotes the statistically significant differences (p < 0.001) between the values of IC50(A2780cis) and IC50(A2780).