Table 3 Inhibitory effects of compounds on ROS production in human whole blood and PMNs
Compound | IC50 μg/mLa) (Whole Blood phagocytes) | IC50 μg/mLa) (PMNs) |
|---|---|---|
1 | 2.3 ± 0.0 | 6.3 ± 0.1 |
2 | 2.0 ± 0.8 | - |
3 | >100 | >50 |
4 | >100 | >50 |
5 | >100 | >50 |
6 | >100 | >50 |
7 | 25.6 | >50 |
Standard (Ibuprofen) | 11.2 ± 1.9 | 2.5 ± 0.6 |