Figure 2
Aggregation curves of inhibitory compounds. Platelet aggregation was performed on human washed platelets. Platelets (0.4 × 109 plt/ml) were treated with increasing concentrations of each inhibitor for 1 min prior to the addition of 25 μM of arachidonic acid for 2 min. Results represent aggregation curves of compound 3 (A), compound 4 (B), compound 7 (C), compound 8 (D), and compound 9 (E). Aggregation curves are representative of at least 4 experiments with similar results.