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Table 4 Performance of PNN for identifying Src inhibitors and non-inhibitors evaluated by 5-fold cross validation study

From: Development and experimental test of support vector machines virtual screening method for searching Src inhibitors from large compound libraries

Cross - validation Src inhibitors Src non-inhibitors Q C
No of training/ testing inhibitors TP FN SE No of training/testing non-inhibitors TN FP SP
1 1362/341 319 22 93.55% 50654/12664 12413 251 98.02% 97.90% 0.715
2 1362/341 324 17 95.01% 50654/12664 12380 284 97.76% 97.69% 0.702
3 1362/341 330 11 96.77% 50654/12664 12395 269 97.88% 97.85% 0.722
4 1363/340 330 10 97.06% 50655/12663 12389 274 97.84% 97.82% 0.720
5 1363/340 318 22 93.53% 50655/12663 12413 250 98.03% 97.91% 0.715
Average     95.19%     97.90% 97.83% 0.715
SD     0.0169     0.0012 0.0009 0.0075
SE     0.0076     0.0005 0.0004 0.0034