Table 6 Application of the proposed method for determination of the studied drugs in spiked and real human plasma
Sample | Concentration taken (ng/mL) | Concentration found (ng/mL) | Recovery % | |||
|---|---|---|---|---|---|---|
Veratic acid | SUL | Veratic acid | SUL | Veratic acid | SUL | |
1-Spiked plasma sample | ||||||
a- Intra-day precision | 10 | 10 | 10.32 | 9.62 | 103.19 | 96.23 |
25 | 50 | 24.34 | 51.04 | 97.36 | 102.09 | |
50 | 100 | 50.28 | 99.50 | 100.55 | 99.50 | |
X' | 100.36 | 99.27 | ||||
± S.D. | 2.92 | 2.95 | ||||
%RSD | 2.91 | 2.95 | ||||
%Error | 1.68 | 1.69 | ||||
b- Inter- day precision | 50 | 100 | 50.56 | 95.32 | 101.12 | 95.30 |
50 | 100 | 51.10 | 98.57 | 102.20 | 98.57 | |
50 | 100 | 49.95 | 101.24 | 99.90 | 101.24 | |
X' | 101.07 | 98.37 | ||||
± S.D. | 1.15 | 2.97 | ||||
%RSD | 1.13 | 3.02 | ||||
%Error | 0.65 | 1.74 | ||||
2- Real plasma sample | 100 | 100 | 91.87 | 92.48 | 91.87 | 92.48 |
100 | 100 | 90.12 | 93.76 | 90.12 | 93.76 | |
100 | 100 | 86.25 | 87.98 | 86.25 | 87.98 | |
X- | 89.41 | 91.40 | ||||
± S.D. | 2.87 | 3.03 | ||||
%RSD | 3.21 | 3.321 | ||||
%Error | 1.85 | 1.91 | ||||