Table 4 The enthalpy of desolvation (T desolv ) of different solvates of ATC
Enthalpy of desolvation, ΔdesolvH (kJ mol−1) from DSC | Enthalpy of desolvation, ΔdesolvH (kJ mol−1) calculated from equation 4 | |
|---|---|---|
Atorvastatin (ATC) | - | |
Solvate- I (ATC + 0.5 Isopropyl alcohol) | 24.20 | 25.93 |
Solvate- II (ATC + THF) | 51.47 | 57.17 |
Solvate- III (ATC + Ethanol) | 44.69 | 34.39 |
Solvate- IV (ATC + 0.5 t-butanol) | 78.85 | 78.31 |
Solvate- V (ATC + methanol) | 26.27 | 26.70 |
Solvate-VI (ATC + 1 Acetone +0.5 Ethanol) | 56.74 | 52.01 |
Solvate-VII (ATC + 0.5 Ethanol + Water) | 104.64 | 103.96 |
Solvate- VIII (ATC + 1- butanol) | 28.56 | 31.81 |