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Table 5 Analysis of CIN in presence of the excipients that are present in its tablets by the proposed method

From: Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate

Excipient

Recovery (% ± SD)a

Pregelatinized starch (50)b

102.09 ± 0.26

Microcrystalline cellulose (50)

102.0 ± 0.57

Povidone (10)

99.28 ± 0.27

Cross povidone (10)

99.25 ± 0.25

Colloidal silicon dioxide (10)

98.34 ± 0.26

Magnesium stearate (10)

101.16 ± 0.95

Average ± SD

100.57 ± 1.51

  1. a Values are mean of three determinations.
  2. b Figures in parenthesis are the amounts in mg added per 30 mg of CIN.