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Table 1 Optimum conditions for the charge-transfer reaction of OLM with PCA

From: Development of a novel 96-microwell assay with high throughput for determination of olmesartan medoxomil in its tablets

Condition

Studied range

Optimum

pCA conc. (%, w/v)

0.1 - 2

0.5

Solvent

Differenta

Acetonitrile

Reaction time (min)

0 - 30

5

Temperature (°C)

25 - 60

25

λmax (nm)

400 - 600

520b

  1. a Solvents tested: methanol, ethanol, 1-propanol, 1-butanol, and acetonitrile.
  2. b Measurements were carried out at 490 nm.