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Table 2 Results obtained by the SIA method and realized by the British Pharmacopoeia method for diclofenac assay in raw materials and pharmaceutical formulations

From: Screening of conditions controlling spectrophotometric sequential injection analysis

Trade name

Formulation

Diclofenac content

Mean recovery ± RSD(%)1

t2

Samf®

Bulk

-

99.3 ± 1.45

2.14

OlfenTM-25

Tablets

25 mg

98.5 ± 2.14

2.06

OlfenTM-50

Tablets

50 mg

98.1 ± 2.81

2.11

Olfen®-75 I.M.

Injection

75 mg in 2 ml

99.1 ± 2.26

1.87

Voltaren®

Gel

1% (w/w)

103.4 ± 3.49

2.23

Diclogesic®

Gel

1% (w/w)

102.7 ± 3.18

2.70

  1. 1: RSD: relative standard deviation for 7 replicates; 2: t-test value