Skip to main content

Table 2 Assay results for the determination of benzophenone in pure forms

From: Derivative spectrophotometric analysis of benzophenone (as an impurity) in phenytoin

Parameter

Proposed method

Comparison method(13)

 

First derivative method (1D)

Third derivative method (3D)

Ratio derivative method (1DD)

 

% Found(a)

098.18

102.35

102.03

100.56

 

100.41

099.84

100.50

099.89

 

100.20

099.63

099.20

100.01

 

100.37

100.12

099.66

 
 

099.81

099.20

100.15

 
 

099.96

100.51

100.11

 

Mean ( x ¯ ) ± S.D.

099.82 ± 0.83

100.27 ± 1.10

100.27 ± 0.97

100.15 ± 0.36

T

0.64

0.18

0.20

 

F

5.48

9.61

7.37

 
  1. a The average of three determinations.
  2. N.B. Tabulated t-value at P = 0.05 is 2.36, tabulated F-value at P = 0.05 is 19.30.