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Table 1 Condensation of A and B under different reaction conditions:

From: Microwave assisted solvent free synthesis of 1,3-diphenylpropenones

Entry Catalyst Catalyst loading a Time (sec) Yieldb(%)
1 None - 100 Trace
2 Al2O3 (neutral) 1:1 100 9
3 Al2O3 (basic) 1:1 100 23
4 Al2O3 (acidic) 1:1 100 27
5 I2 10 100 63
6 I2 20 100 65
7 I2 50 100 61
8 I2-Al2O3 (basic) 1:1 100 67
9 I2-Al2O3 (neutral) 1:1 100 94
10 I2-Al2O3 (neutral) 1:1 300 Trace c
11 I2-Al2O3 (acidic) 1:1 100 71
12 I2-Al2O3 (neutral) 2:1 100 69
13 I2-Al2O3 (neutral) 2:1 150 69
14 I2-Al2O3 (neutral) 2:1 300 71
15 I2-Al2O3 (neutral) 1:2 80 94
16 I2-Al2O3 (neutral) 1:2 60 81
  1. a For entry 5-7, catalyst loading is in mol%. For others it is given as substrate (A): catalyst (w/w).
  2. b Isolated pure yield; unreacted starting materials recovered.
  3. c The reaction mixture was kept in a preheated oil bath at 60°C for the specified time.