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Table 5 Application of the proposed method for determination of the studied drugs in their co-formulated preparation

From: Synchronous fluorescence spectrofluorimetric method for the simultaneous determination of metoprolol and felodipine in combined pharmaceutical preparation

Preparation Concentration taken (μg/mL) Concentration found (μg/mL) Recovery % Comparison method (4)
  MTP FDP MTP FDP MTP FDP MTP FDP
Logimax ® Tablets a 5.0 0.5 4.919 0.503 98.37 100.62 98.82 99.36
(MTP 50 mg + FDP 5 mg/Tablet) 8.0 0.8 7.927 0.813 99.09 101.65 101.79 100.84
Batch # 604346 10.0 1.0 9.907 1.002 99.07 100.17 99.28 99.69
(x)      98.84 100.81 99.96 99.96
± SD      ± 0.41 ± 0.759 ± 1.6 ± 0.78
% RSD      0.415 0.753   
% Error      0.24 0.435   
t      1.18 (2.78) 1.36(2.78)   
F      15.2 (19) 1.05 (19)   
  1. • Each result is the average of three separate determinations. aProduct of Astra Zeneca.
  2. • Figures between parenthesis are the tabulated t (at degree of freedom = 4 for both drugs) and F values (at degree of freedom = 2, 2 for both drugs), respectively at p = 0.05 [11].