Table 5 Application of the proposed method for determination of the studied drugs in their co-formulated preparation
Preparation | Concentration taken (μg/mL) | Concentration found (μg/mL) | Recovery % | Comparison method (4) | ||||
|---|---|---|---|---|---|---|---|---|
MTP | FDP | MTP | FDP | MTP | FDP | MTP | FDP | |
Logimax ® Tablets a | 5.0 | 0.5 | 4.919 | 0.503 | 98.37 | 100.62 | 98.82 | 99.36 |
(MTP 50 mg + FDP 5 mg/Tablet) | 8.0 | 0.8 | 7.927 | 0.813 | 99.09 | 101.65 | 101.79 | 100.84 |
Batch # 604346 | 10.0 | 1.0 | 9.907 | 1.002 | 99.07 | 100.17 | 99.28 | 99.69 |
(x) | 98.84 | 100.81 | 99.96 | 99.96 | ||||
± SD | ± 0.41 | ± 0.759 | ± 1.6 | ± 0.78 | ||||
% RSD | 0.415 | 0.753 | ||||||
% Error | 0.24 | 0.435 | ||||||
t | 1.18 (2.78) | 1.36(2.78) | ||||||
F | 15.2 (19) | 1.05 (19) | ||||||