Synchronous fluorescence spectrofluorimetric method for the simultaneous determination of metoprolol and felodipine in combined pharmaceutical preparation

Table 1 Performance data of the determination of MTP and FLD in pure form by the proposed method

Parameter	Metoprolol	Felodipine
Concentration range (μg/mL)	0.5-10.0	0.2-2.0
Correlation coefficient	0.9999	0.9999
Slope	56.36	164.51
Intercept	11.12	7.15
Limit of detection (LOD) (μg/mL)	0.11	0.02
Limit of Quantification (LOQ) (μg/mL)	0.32	0.06
S_y/x	2.87	1.31
S_a	1.82	0.91
S_b	0.33	0.91
%RSD	1.49	1.17
%Er	0.61	0.48

ISSN: 2661-801X