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Table 4 Recovery studies with pregabalin capsules by standard addition method

From: A novel method for spectrophotometric determination of pregabalin in pure form and in capsules

Initial Conc. (mg/mL)

Volume (mL)

Amount of PGB added (μg)

Amount recovered (μg)

Recovery (%) ± SDa

Er%

RSD (%)

0.05

5.0

50.0

49.5

98.85 ± 0.145

-1.14

0.14

0.05

5.0

100.0

99.5

99.09 ± 0.370

-0.91

0.37

0.05

5.0

200.0

199.1

99.45 ± 0.124

-0.550

0.13

0.1

5.0

50.0

49.1

98.71 ± 0.471

-1.29

0.47

0.1

5.0

100.0

98.1

98.16 ± 0.271

-1.83

0.28

0.1

5.0

200.0

98.1

98.16 ± 0.271

-1.83

0.28

0.2

5.0

50.0

49.0

98.44 ± 0.426

-1.55

0.43

0.2

5.0

100.0

99.7

99.67 ± 0.186

-0.32

0.19

0.2

5.0

200.0

199.0

99.49 ± 0.165

-0.510

0.17

0.4

5.0

50.0

49.7

99.27 ± 0.251

-0.73

0.25

0.4

5.0

100.0

97.6

97.54 ± 0.196

-2.45

0.20

0.4

5.0

200.0

199.7

99.74 ± 0.123

-0.253

0.12

0.6

5.0

50.0

49.8

99.07 ± 0.483

-0.92

0.48

0.6

5.0

100.0

98.2

98.29 ± 0.134

-1.70

0.14

0.6

5.0

200.0

198.9

98.71 ± 0.646

-1.287

0.65

0.8

5.0

50.0

49.1

98.62 ± 0.479

-1.38

0.48

0.8

5.0

100.0

99.2

99.25 ± 0.098

-0.74

0.10

0.8

5.0

200.0

198.2

99.22 ± 0.136

-0.777

0.14

1.0

5.0

50.0

50.0

99.49 ± 0.495

-0.51

0.49

1.0

5.0

100.0

97.0

97.09 ± 0.147

-2.91

0.15

1.0

5.0

200.0

199.5

99.66 ± 0.198

-0.333

0.20

  1. a Average of determinations carried out in triplicate.