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Table 1 Validation data for determination of pregabalin by proposed method

From: A novel method for spectrophotometric determination of pregabalin in pure form and in capsules

Validation parameter

Results

Absorption maximum

402.6 nm

Regression equation

y = 1.908x - 0.056

Slope

1.908

Intercept

0.056

Beer's law limit (μg mL-1)

50-1000

Molar Absorptivity (L/mol-1/cm-1)

1198.4

Sandell's sensitivity (μg/cm2/0.001 A.U)

0.1328

Coefficient of correlation(r)

0.992

Limit of detection (LOD)

0.006 mg/mL

Limit of quantification (LOQ)

0.02 mg/mL

Accuracy

100.43 ± 1.24

Precision

Intra-day = 0.62

 

Inter-day = 0.61

Robustness

Less than 1%

% Purity

99.8%