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Table 2 Synthesis of N-substituted isatin derivatives

From: Simple isatin derivatives as free radical scavengers: Synthesis, biological evaluation and structure-activity relationship

Compound R Time (h) Yield (%)
1 H _ _
2 CH3 4 87
3 C2H5 12 89
4 (CH2)2CH3 12 89
5 (CH2)3CH3 24 93
6 (CH2)4CH3 24 90
7 (CH2)5CH3 24 95
8 CH2CH = CH2 12 93
9 CH2C6H5 12 90
10 CH2COOC2H5 12 93
11 C2H4Cl 24 79
12 C2H4Br 24 83