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Table 1 The substitution reaction between isatin and bromoethane

From: Simple isatin derivatives as free radical scavengers: Synthesis, biological evaluation and structure-activity relationship

No.

Solvent

Base

Time (h)

Yield (%)

1

DMF

Na2CO3

24

33

2

DMF

K2CO3

12

89

3

DMF

NaOH

12

40

4

DMF

KOH

12

41

5

DMF

TEA

24

60

6

MeOH

K2CO3

24

12

7

THF

K2CO3

24

25

8

DCM

K2CO3

24

19

9

Acetonitrile

K2CO3

24

15

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BMC Chemistry

ISSN: 2661-801X

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