|
Pharmaceutical preparation
|
Method I
|
Method II
|
Comparison method [3]
|
|---|
| |
Conc. taken (μg mL-1)
|
% Found
|
Conc. taken (μg mL-1)
|
% Found
| |
|---|
|
Lyrica
®
Capsules
|
8.0
|
99.91
|
3.0
|
100.45
|
101.01
|
|
(75 mg PG/capsule)
b
|
15.0
|
99.41
|
4.0
|
101.11
|
99.43
|
| |
20.0
|
98.01
|
6.0
|
98.78
|
99.3
|
|
99.11 ± 0.98
|
100.11 ± 1.20
|
99.91 ± 0.95
|
|
T
|
1.016 (2.776)a
|
0.226 (2.776)a
| |
|
F
|
1.070 (19.00)a
|
1.591 (19.00)a
| |
|
Nominal content of capsule(75 mg)
|
74.33 ± 0.74
|
74.08 ± 0.90
| |
- Each result is the average of three separate determinations.
- a Values between brackets are the tabulated t and F values, at p = 0.05 [33].
- b Product of Pfizer (Batch No: 0744019 and Exp date: 10/2010)
