Table 5 Determination of ebastine in its dosage forms by the proposed HPLC method
Proposed method | Comparison method [4] | |||
|---|---|---|---|---|
Preparation | Amount taken (μg/ml) | Amount found (μg/ml) | % Recovery | % Recovery |
Bastab ® tablets | 0.3 | 0.2974 | 99.14 | 99.23 |
0.7 | 0.6981 | 99.72 | 99.61 | |
1.0 | 1.0094 | 100.94 | 100.61 | |
3.0 | 3.0036 | 100.12 | ||
5.0 | 4.9835 | 99.67 | ||
6.0 | 5.9844 | 99.74 | ||
Xˉ ± SD | 99.88 ± 0.61 | 99.82 ± 0.71 | ||
Student's t test | 0.39(2.02)* | |||
Variance ratio F test | 1.35(3.78)* | |||
Evastine ® syrup | 0.3 | 0.30216 | 100.72 | 100.12 |
0.7 | 0.69615 | 99.45 | 99.61 | |
1.0 | 1.0011 | 100.11 | 99.51 | |
3.0 | 3.0144 | 100.48 | ||
5.0 | 5.031 | 100.62 | ||
6.0 | 5.9994 | 99.99 | ||
Xˉ ± SD | 100.23 ± 0.48 | 99.75 ± 0.33 | ||
Student's t test | 0.23(2.02)* | |||
Variance ratio F test | 2.12(3.78)* | |||