Table 4 Validation of the proposed HPLC method for determination of ebastine in pure and dosage forms
Preparation | Repeatability, % Recovery | Intermediate precision, %Recovery |
|---|---|---|
Ebastine pure form | Ebastine (5.0 μg/ml) | Ebastine (6.0 μg/ml) |
99.95 | 100.95 | |
100.25 | 100.38 | |
100.54 | 99.65 | |
100.87 | 99.12 | |
Xˉ ± SD | 100.41 ± 0.39 | 100.03 ± 0.81 |
Bastab ® tablets | Ebastine (0.3 μg/ml) | Ebastine (4.0 μg/ml) |
99.65 | 99.35 | |
99.84 | 99.98 | |
100.58 | 100.87 | |
100.68 | 100.92 | |
Xˉ ± SD | 100.19 ± 0.52 | 100.28 ± 0.76 |
Evastine ® syrup | Ebastine (2.0 μg/ml) | Ebastine (3.0 μg/ml) |
100.14 | 99.32 | |
100.55 | 100.84 | |
100.92 | 100.99 | |
99.64 | 100.06 | |
Xˉ ± SD | 100.31 ± 0.55 | 100.31 ± 0.77 |