Table 6 Validation of the proposed methods for the determination o0f ebastine in pure and dosage forms

Ebastine pure form

Ebastine (0.5 μg/ml)

Ebastine (0.1 μg/ml)

Ebastine (0.3 μg/ml)

Ebastine (0.7 μg/ml)

99.62

100.25

100.66

99.54

99.24

100.65

100.06

99.35

100.65

100.87

100.97

100.15

100.25

99.95

99.86

99.42

Xˉ ± SD

99.94 ± 0.63

100.43 ± 0.41

100.39 ± 0.52

99.62 ± 0.37

Bastab ^® tablets containing 20 mg ebastine/tablet

Ebastine (0.8 μg/ml)

Ebastine (0.3 μg/ml)

Ebastine (0.1 μg/ml)

Ebastine (0.5 μg/ml)

100.12

100.65

100.45

99.12

100.36

100.22

100.68

99.54

99.21

99.87

99.06

99.35

99.85

99.54

99.54

100.24

Xˉ ± SD

99.89 ± 0.61

100.07 ± 0.48

99.93 ± 0.76

99.56 ± 0.48

Evastine ^® syrup containing 5 mg Ebastine/5ml

Ebastine (1.0 μg/ml)

Ebastine (0.4 μg/ml)

Ebastine (0.2 μg/ml)

Ebastine (0.6 μg/ml)

100.98

100.65

100.54

99.65

100.45

100.15

100.98

99.15

99.32

100.98

99.48

100.54

99.15

100.11

99.72

100.32

Xˉ ± SD

99.98 ± 0.88

100.47 ± 0.42

100.18 ± 0.7

99.92 ± 0.64