Table 1 Gold amount in the mouse liver following five intratracheal instillations detected with ICPMS.
From: Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation
Animal number | Particles used for instillations | Total amount/volume given | Amount of gold traced in the liver | Level of the gold in the liver compared with the total amount given |
|---|---|---|---|---|
1. | 2 nm Au | 3025 ng | 4 ng | 1.3‰ |
2. | 2 nm Au | 3025 ng | 4.1 ng | 1.4‰ |
3. | 40 nm Au | 14550 ng | < 2 ng | 0 |
4. | 40 nm Au | 14550 ng | < 2 ng | 0 |
5. | 40 nm Au | 14550 ng | < 2 ng | 0 |
6. | 40 nm Au | 14550 ng | 43.4 ng | 3‰ |
7. | 100 nm Au | 15025 ng | 5.8 ng | 0.39‰ |
8. | 100 nm Au | 15025 ng | < 2 ng | 0 |
9. | 100 nm Au | 15025 ng | < 2 ng | 0 |
10. | 100 nm Au | 15025 ng | < 2 ng | 0 |
11. | 100 nm Au | 15025 ng | < 2 ng | 0 |
12. | H2O | 250 μl | < 2 ng | |
13. | H2O | 250 μl | < 2 ng | |
14. | H2O | 250 μl | < 2 ng | |
15. | H2O | 250 μl | < 2 ng | |
16. | H2O | 250 μl | < 2 ng |