Light and electron micrographs showing AMG enhanced gold nanoparticles in the lungs of mice following intratracheal instillations. A and B represent LM section taken from the animals exposed to multiple intratracheal instillations with gold, 40 nm and 100 nm nanoparticles, respectively. AMG enhanced gold nanoaparticles are located inside lung macrophages resembling cells. C represents a control, void of AMG staining. D and E are EM picture representing the animals exposed to multiples instillations with 40 nm gold nanoparticles. Gold is located inside lysosome/endosome-like vesicles. Scalebars: 20 μm in A - C; 1 μm in D; 500 nm in E.