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Table 1 Some examples of different functions and localizations of GAPDH.

From: Finding one's way in proteomics: a protein species nomenclature

Function/Cellular role

Localization

PTM*

Interaction partner

Reference

Apoptosis (Figure 4)

Nucleus

Nitrosylation

Siah

[36]

Plasma membrane fusion

Membrane

-

Anion exchanger protein

[37]

Microtubule structure and function

Cytoplasm

-

Tubulin

[38]

Translational regulation

-

-

5V and 3VUTR mRNA sequence

[39]

Cell transport properties

Secretory vesicles

Phosphorylation

PKCL/E

[40]

Transcription control

Nucleus

-

Oct-1 transcription factor +

promyelocytic leukemia

nuclear bodies

[41]

[42]

 

Nucleus

-

Telomeres

[43]

Intranuclear transport

Nucleus

-

tRNA precursors

[44]

Cell proliferation

-

-

Ap4A

[45, 46]

Nuclear membrane

fusion

Nuclear envelope

-

-

[47]

  1. *post-translational modification