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Table 5 Determination of ETD in pharmaceutical preparations using the proposed methods.

From: Spectrophotometric determination of etodolac in pure form and pharmaceutical formulations

Sample

  

Recoverya ± SD (%)

  

Official method

Proposed methods

   

A

B

C

Napilac capsules (200 mg ETD/Capsule)

X ± SD

99.70 ± 1.16

98.52 ± 0.79

100.65 ± 1.19

100.27 ± 0.92

 

t b

 

1.87

0.74

0.86

 

F b

 

2.17

1.05

1.60

Etodine capsules (300 mg ETD/Capsule)

X ± SD

100.50 ± 1.36

99.95 ± 0.81

100.30 ± 0.96

100.04 ± 1.02

 

t b

 

0.78

0.27

0.61

 

F b

 

2.82

2.01

1.78

  1. a Average of six determinations.
  2. b The theoretical t- and F-values, 2.571 and 6.256, respectively for five degree of freedom at 95% confidence level.