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Table 5 Determination of ETD in pharmaceutical preparations using the proposed methods.

From: Spectrophotometric determination of etodolac in pure form and pharmaceutical formulations

Sample    Recoverya ± SD (%)
   Official method Proposed methods
    A B C
Napilac capsules (200 mg ETD/Capsule) X ± SD 99.70 ± 1.16 98.52 ± 0.79 100.65 ± 1.19 100.27 ± 0.92
  t b   1.87 0.74 0.86
  F b   2.17 1.05 1.60
Etodine capsules (300 mg ETD/Capsule) X ± SD 100.50 ± 1.36 99.95 ± 0.81 100.30 ± 0.96 100.04 ± 1.02
  t b   0.78 0.27 0.61
  F b   2.82 2.01 1.78
  1. a Average of six determinations.
  2. b The theoretical t- and F-values, 2.571 and 6.256, respectively for five degree of freedom at 95% confidence level.