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Table 3 Determination of ETD in presence of additives or excipients.

From: Spectrophotometric determination of etodolac in pure form and pharmaceutical formulations

Material

Amount (mg)

Method A

Method B

Method C

  

Recovery a %± SD b

Recovery a %± SD b

Recovery a %± SD b

Lactose

50

99.63 ± 0.82

99.20 ± 0.78

100.2 ± 0.51

Glucose

50

98.84 ± 0.67

100.35 ± 1.22

99.55 ± 0.88

Dextrose

50

99.30 ± 0.78

98.70 ± 0.56

98.65 ± 0.46

Magnesium stearate

30

99.25 ± 0.75

99.55 ± 0.89

100.15 ± 1.30

Calcium hydrogen phosphate

50

99.50 ± 0.96

98.95 ± 0.73

99.40 ± 0.84

Talc

40

99.80 ± 0.61

100.40 ± 1.05

100.10 ± 0.95

Starch

50

100.05 ± 1.14

98.80 ± 0.69

99.75 ± 0.62

  1. a 6.0 μg mL-1 of ETD was taken.
  2. b Average of five determinations.
  3. SD: Standard deviation.